解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Ocular images play an essential role in ophthalmological diagnoses. Having an imbalanced dataset is an inevitable issue in automated ocular diseases diagnosis; the scarcity of positive samples always tends to result in the misdiagnosis of severe patients during the classification task. Exploring an effective...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0420-1
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the ex...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0419-7
更新日期:2017-11-13 00:00:00
abstract:BACKGROUND:Gene expression analyses demand appropriate reference genes (RGs) for normalization, in order to obtain reliable assessments. Ideally, RG expression levels should remain constant in all cells, tissues or experimental conditions under study. Housekeeping genes traditionally fulfilled this requirement, but the...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0356-5
更新日期:2017-08-18 00:00:00
abstract:BACKGROUND:Neural stimulation is an important method used to activate or inhibit action potentials of the neuronal anatomical targets found in the brain, central nerve and peripheral nerve. The neural stimulator system produces biphasic pulses that deliver balanced charge into tissue from single or multichannel electro...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0385-0
更新日期:2017-08-14 00:00:00
abstract:OBJECTIVE:To evaluate the in vivo and in vitro performance of a China-made dialysis machine (SWS-4000). METHODS:This was a multi-center prospective controlled study consisting of both long-term in vitro evaluations and cross-over in vivo tests in 132 patients. The China-made SWS-4000 dialysis machine was compared with...
journal_title:Biomedical engineering online
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/s12938-017-0387-y
更新日期:2017-08-02 00:00:00
abstract:BACKGROUND:Studies have identified hemodynamic shear stress as an important determinant of endothelial function and atherosclerosis. In this study, we assess the influences of hemodynamic shear stress on carotid plaques. METHODS:Carotid stenosis phantoms with three severity (30, 50, 70%) were made from 10% polyvinyl a...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0386-z
更新日期:2017-07-29 00:00:00
abstract:BACKGROUND:Mechanobiological studies allow the characterization of cell response to mechanical stresses. Cells need to be supported by a material with properties similar to the physiological environment. Silicone elastomers have been used to produce various in vitro scaffolds of different geometries for endothelial cel...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0380-5
更新日期:2017-07-14 00:00:00
abstract::Current clinically accepted technologies for cancer treatment still have limitations which lead to the exploration of new therapeutic methods. Since the past few decades, the hyperthermia treatment has attracted the attention of investigators owing to its strong biological rationales in applying hyperthermia as a canc...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-017-0327-x
更新日期:2017-03-23 00:00:00
abstract:BACKGROUND:Endovascular intervention using a stent is a mainstream treatment for cerebral aneurysms. To assess the effect of intervention strategies on aneurysm hemodynamics, we have developed a fast virtual stenting (FVS) technique to simulate stent deployment in patient-specific aneurysms. However, quantitative valid...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0250-6
更新日期:2016-12-28 00:00:00
abstract:BACKGROUND:In stent design optimization, the functional relationship between design parameters and design goals is nonlinear, complex, and implicit and the multi-objective design of stents involves a number of potentially conflicting performance criteria. Therefore it is hard and time-consuming to find the optimal desi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0268-9
更新日期:2016-12-28 00:00:00
abstract:BACKGROUND:Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0274-y
更新日期:2016-12-28 00:00:00
abstract:BACKGROUND:Tumor hypoxia is involved in every stage of solid tumor development: formation, progression, metastasis, and apoptosis. Two types of hypoxia exist in tumors-chronic hypoxia and acute hypoxia. Recent studies indicate that the regional hypoxia kinetics is closely linked to metastasis and therapeutic responses,...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0235-5
更新日期:2016-10-12 00:00:00
abstract:BACKGROUND:Since hemodynamics plays a key role in the development and evolution of cardiovascular pathologies, physician's decision must be based on proper monitoring of relevant physiological flow quantities. METHODS:A numerical analysis of the error introduced by an intravascular Doppler guide wire on the peak veloc...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0234-6
更新日期:2016-10-10 00:00:00
abstract:BACKGROUND:Inhaled nitric oxide (NO) is a selective pulmonary vasodilator used primarily in the critical care setting for patients concurrently supported by invasive or noninvasive positive pressure ventilation. NO delivery devices interface with ventilator breathing circuits to inject NO in proportion with the flow of...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0227-5
更新日期:2016-08-30 00:00:00
abstract:BACKGROUND AND AIMS:People with internet addiction (IA) suffer from mental, physical, social, and occupational problems. IA includes psychological and physiological syndromes, and among the syndromes, emotion was suggested important mental and physiological expressions of IA. However, few physiologically emotional char...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0201-2
更新日期:2016-07-04 00:00:00
abstract:BACKGROUND:In order to reduce the radiation dose of CT (computed tomography), compressed sensing theory has been a hot topic since it provides the possibility of a high quality recovery from the sparse sampling data. Recently, the algorithm based on DL (dictionary learning) was developed to deal with the sparse CT reco...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0193-y
更新日期:2016-06-18 00:00:00
abstract:BACKGROUND:Robot-based joint-testing systems (RJTS) can be used to perform unconstrained laxity tests, measuring the stiffness of a degree of freedom (DOF) of the joint at a fixed flexion angle while allowing the other DOFs unconstrained movement. Previous studies using the force-position hybrid (FPH) control method pr...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0195-9
更新日期:2016-06-07 00:00:00
abstract:BACKGROUND:Robot-assisted laparoscopic surgery offers several advantages compared with open surgery and conventional minimally invasive surgery. However, one issue that needs to be resolved is a collision between the robot arm and the assistant instrument. This is mostly caused by miscommunication between the surgeon a...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0189-7
更新日期:2016-05-20 00:00:00
abstract:BACKGROUND:Frequency selectivity (FS) of the auditory system is established at the level of the cochlea and it is important for the perception of complex sounds. Although direct measurements of cochlear FS require surgical preparation, it can also be estimated with the measurements of otoacoustic emissions or behaviora...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0167-0
更新日期:2016-05-10 00:00:00
abstract:BACKGROUND:The emergence and development of robot assistant interventional vascular surgery technologies have benefited many patients with cardiovascular or cerebrovascular diseases. Due to the absence of effective training measures, these new advanced technologies have not been fully utilized and only few experienced ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0148-3
更新日期:2016-04-06 00:00:00
abstract:BACKGROUND:Areas with high frequency activity within the atrium are thought to be 'drivers' of the rhythm in patients with atrial fibrillation (AF) and ablation of these areas seems to be an effective therapy in eliminating DF gradient and restoring sinus rhythm. Clinical groups have applied the traditional FFT-based a...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0143-8
更新日期:2016-03-08 00:00:00
abstract:BACKGROUND:Sleep apnea (OSA) is a common sleep disorder characterized by recurring breathing pauses during sleep caused by a blockage of the upper airway (UA). The altered UA structure or function in OSA speakers has led to hypothesize the automatic analysis of speech for OSA assessment. In this paper we critically rev...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0138-5
更新日期:2016-02-20 00:00:00
abstract:BACKGROUND:The biomechanical simulation of the human respiratory system is expected to be a useful tool for the diagnosis and treatment of respiratory diseases. Because the deformation of the thorax significantly influences airflow in the lungs, we focused on simulating the thorax deformation by introducing contraction...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0132-y
更新日期:2016-02-06 00:00:00
abstract:BACKGROUND:Magneto-acoustic tomography with current injection involves using electrical impedance imaging technology. To explore the potential applications in imaging biological tissue and enhance image quality, a new scan mode for the transducer is proposed that is based on translational and circular scanning to recor...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0125-x
更新日期:2016-01-27 00:00:00
abstract:BACKGROUND:The low quality of diffusion tensor image (DTI) could affect the accuracy of oncology diagnosis. METHODS:We present a novel sparse representation based denoising method for three dimensional DTI by learning adaptive dictionary with the context redundancy between neighbor slices. In this study, the context r...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0116-3
更新日期:2016-01-13 00:00:00
abstract:BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0112-7
更新日期:2015-12-21 00:00:00
abstract:BACKGROUND:Nonnegative matrix factorization (NMF) has been used in blind fluorescence unmixing for multispectral in-vivo fluorescence imaging, which decomposes a mixed source data into a set of constituent fluorescence spectra and corresponding concentrations. However, most classical NMF algorithms have ill convergence...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0107-4
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:Phase contrast magnetic resonance imaging (PC-MRI) is used clinically for quantitative assessment of cardiovascular flow and function, as it is capable of providing directly-measured 3D velocity maps. Alternatively, vascular flow can be estimated from model-based computation fluid dynamics (CFD) calculations...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0104-7
更新日期:2015-11-26 00:00:00
abstract:BACKGROUND:This work deals with copyright protection of digital images, an issue that needs protection of intellectual property rights. It is an important issue with a large number of medical images interchanged on the Internet every day. So, it is a challenging task to ensure the integrity of received images as well a...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0101-x
更新日期:2015-11-25 00:00:00
abstract:BACKGROUND:One of the recommended treatments for disorders associated with the lower extremity venous insufficiency is the application of external mechanical compression. Compression stockings and elastic bandages are widely used for the purpose of compression therapy and are usually designed to exert a specified value...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0088-3
更新日期:2015-11-05 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) and essential tremor (ET) are the two most common movement disorders but the rate of misdiagnosis rate in these disorders is high due to similar characteristics of tremor. The purpose of the study is to present: (a) a solution to identify PD and ET patients by using the novel measure...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0098-1
更新日期:2015-11-04 00:00:00
abstract:BACKGROUND:The gait movement is an essential process of the human activity and the result of collaborative interactions between the neurological, articular and musculoskeletal systems, working efficiently together. This explains why gait analysis is important and increasingly used nowadays for the diagnosis of many dif...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0097-2
更新日期:2015-10-29 00:00:00
abstract:BACKGROUND:It is a known fact that blood flow pattern and more specifically the pulsatile time variation of shear stress on the vascular wall play a key role in atherogenesis. The paper presents the conception, the building and the control of a new in vitro test bench that mimics the pulsatile flows behavior based on i...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0065-x
更新日期:2015-08-07 00:00:00
abstract:BACKGROUND:Classification of breast ultrasound (BUS) images is an important step in the computer-aided diagnosis (CAD) system for breast cancer. In this paper, a novel phase-based texture descriptor is proposed for efficient and robust classifiers to discriminate benign and malignant tumors in BUS images. METHOD:The p...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0022-8
更新日期:2015-03-24 00:00:00
abstract:BACKGROUND:The pupillary light reflex characterizes the direct and consensual response of the eye to the perceived brightness of a stimulus. It has been used as indicator of both neurological and optic nerve pathologies. As with other eye reflexes, this reflex constitutes an almost instantaneous movement and is linked ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0016-6
更新日期:2015-03-13 00:00:00
abstract:BACKGROUND:Routine vascular surgery operations involve stitching of disconnected human arteries with themselves or with artificial grafts (arterial anastomosis). This study aims to extend current knowledge and provide better-substantiated understanding of the mechanics of end-to-end anastomosis through the development ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-1
更新日期:2015-01-06 00:00:00
abstract:BACKGROUND:For electroporation-based therapies, accurate modeling of the electric field distribution within the target tissue is important for predicting the treatment volume. In response to conventional, unipolar pulses, the electrical impedance of a tissue varies as a function of the local electric field, leading to ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-S3-S3
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Electrochemotherapy (ECT) is a combined treatment in which high voltage electroporation (EP) pulses are used to facilitate the uptake of a chemotherapeutic drug into tumor cells, thus increasing antitumor effectiveness of the drug. The effect of ECT of deep-seated tumors located close to the heart on functio...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-S3-S5
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Studies found that treatment symptoms of concern to oncology/hematology patients were greatly under-identified in medical records. On average, 11.0 symptoms were reported of concern to patients compared to 1.5 symptoms identified in their medical records. A solution to this problem is use of an electronic sy...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-S2-S1
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:In literature, the effect of the inflow boundary condition was investigated by examining the impact of the waveform and the shape of the spatial profile of the inlet velocity on the cardiac hemodynamics. However, not much work has been reported on comparing the effect of the different combinations of the inl...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-S1-S6
更新日期:2015-01-01 00:00:00